○第一著者もしくは応答著者の論文


35. Lahiru N. Jayakody, Jannatul Ferdouse, Nobuyuki Hayashi, Hiroshi Kitagaki*
Identification and detoxification of glycolaldehyde, an unattended bioethanol fermentation inhibitor.
Critical Reviews in Biotechnology, 37(2):177-189 (2017). doi: 10.3109/07388551.2015.1128877.

34. Jannatul Ferdouse、阪本真由子、酒谷真以、浜島浩史、松永陽香、柘植圭介、西向めぐみ、柳田晃良、永尾晃治、光武進、北垣浩志*
?麹で造られる醸造食品のグリコシルセラミド含量定量手法の検討とそれを用いた定量
日本醸造学会誌、in press (2017).
Jannatul Ferdouse、Mayuko Sakamoto, Mai Sakatani, Hiroshi Hamajima, Keisuke Tsuge, Megumi Nishimukai, Teruyoshi Yanagita, Koji Nagao, Susumu Mitsutake, and Hiroshi Kitagaki*
Development of a quantitative method for the contents of glycosylceramide contained in Japanese foods brewed with koji and its application.
Journal of the Brewing Society of Japan, in press (2017)

33. Hiroshi Hamajima, Haruka Matsunaga; Ayami Fujikawa; Tomoya Sato; Susumu Mitsutake; Teruyoshi Yanagita; Koji Nagao; Jiro Nakayama; Hiroshi Kitagaki*.
Japanese Traditional Dietary Fungus Koji Aspergillus oryzae Functions as a Prebiotic for Blautia Coccoides through Glycosylceramide.
SpringerPlus, 5, 1321 (2016)(日本農芸化学会トピックス賞)

32. Kazutaka Sawada and Hiroshi Kitagaki*
Residual mitochondrial transmembrane potential decreases unsaturated fatty acid level in sake yeast during alcoholic fermentation.
PeerJ, 4, 1522 (2015)

31. Hiroshi Hamajima, Ayumi Fujikawa, Mikako Yamashiro, Takatoshi Ogami, Seiichi Kitamura, Masahito Tsubata, Sei Tan, Haruka Matsunaga, Kazutaka Sawada, Satoshi Kumagai, Nobuyuki Hayashi, Koji Nagao, Teruyoshi Yanagita, Takuji Oka, Susumu Mitsutake and Hiroshi Kitagaki*
Chemical analysis of the sugar moiety of monohexosylceramide contained in koji, Japanese traditional rice fermented with Aspergillus.
Fermentation, 2016, 2(1), 2; doi:10.3390/fermentation2010002

30. Lahiru N. Jayakody, Jannatul Ferdouse, Nobuyuki Hayashi, Hiroshi Kitagaki*
Identification and detoxification of glycolaldehyde, an unattended bioethanol fermentation inhibitor.
Critical Reviews in Biotechnology, in press (2015)

29. Kazutaka Sawada, Tomoya Sato, Hiroshi Hamajima, Lahiru Niroshan Jayakody, Miyo Hirata, Mikako Yamashiro, Marie Tajima, Susumu Mitsutake, Koji Nagao, Keisuke Tsuge, Fumiyoshi Abe, Kentaro Hanada, and Hiroshi Kitagaki*
Glucosylceramide contained in Koji mold-cultured cereal confers membrane and flavor modification and stress tolerance to Saccharomyces cerevisiae during coculture fermentation.
Applied and Environmental Microbiology, 81(11):3688-98. doi: 10.1128/AEM.00454-15 (2015) 日本農芸化学会誌 化学と生物で注目記事に選定

28. Lahiru N. Jayakody, Masafumi Kadowaki, Keisuke Tsuge, Kenta Horie, Akihiro Suzuki, Nobuyuki Hayashi, and Hiroshi Kitagaki*
SUMO expression shortens the lag phase of Saccharomyces cerevisiae yeast growth caused by complex interactive effects of major mixed fermentation inhibitors found in hot-compressed water-treated lignocellulosic hydrolysate.
Appl. Microbiol. Biotechnol., 99, 1, pp 501-515 (2015) Key Scientific Article in Renewable Energy Global Innovations カナダの再生可能エネルギージャーナルでハイライト論文に選定

27. 澤田和敬、中畑絵里子、柘植圭介、平田みよ、峯和則、永尾晃治、北垣浩志*
エレクトロスプレーイオン化質量分析(ESI-MS/MS)による芋焼酎粕に含まれるグルコシルセラミドの構造決定
日本醸造学会誌, 109, 7, 535-542 (2014)

26. Shodai Shiroma, Lahiru Niroshan Jayakody, Kenta Horie, Koji Okamoto and Hiroshi Kitagaki*
Enhancement of ethanol fermentation of Saccharomyces cerevisiae sake yeast strain by disrupting mitophagy function.
Applied and Environmental Microbiology, 80 (3), 1002-1012 (2014) (日本農芸化学会トピックス賞)

25. Koshiro Takahashi, Kazuki Izumi, Eriko Nakahata, Miyo Hirata, Kazutaka Sawada, Keisuke Tsuge, Koji Nagao and Hiroshi Kitagaki*
Quantitation and structural determination of glucosylceramides contained in sake lees.
Journal of Oleo Science, 63, 1, 15-23 (2014)

24. Lahiru N. Jayakody, Kenta Horie, Nobuyuki Hayashi and
Hiroshi Kitagaki*

Engineering redox cofactor utilization for detoxification of glycolaldehyde, a key inhibitor of bioethanol production, in yeast Saccharomyces cerevisiae.
Applied Microbiology and Biotechnology, 97(14):6589-600 (2013)


23.Lahiru N. Jayakody, Keisuke Tsuge, Akihiro Suzuki, Hitoshi Shimoi and Hiroshi Kitagaki*
Identification of sulfate ion as one of the key component of yeast spoilage of a sports drink through genome-wide expression analysis.

  Journal of General and Applied Microbiology, 59(3):227-238 (2013)

22. Hiroshi Kitagaki* and Katsuhiko Kitamoto


Breeding researches of sake yeasts in Japan: History, recent technological advances, and future perspectives.

Annual Review of Food Science and Technology, 4, 215-235 (2013) 
YOU CAN ACCESS YOUR ARTICLE VIA THE FOLLOWING E-PRINT URL: http://arjournals.annualreviews.org/eprint/pcwz7Bgce8MBsBfICUcb/full/10.1146/annurev-food-030212-182545. 


21. Structural determination of glucosylceramides in the distillation remnants of shochu, the Japanese traditional liquor, and its production by Aspergillus kawachii.


  Miyo Hirata, Keisuke Tsuge, Lahiru Jayakody, Yoshitaka Urano, Kazutaka Sawada, Shigeki Inaba, Koji Nagao and Hiroshi Kitagaki*
  Journal of Agricultural and Food Chemistry, 60 (46) 11473-82 (2012)
(日本醸造協会技術賞)


20. Breeding of a high tyrosol-producing sake yeast by isolation of an ethanol-resistant mutant from trp3 mutant.
Hisayoshi Soejima, Keisuke Tsuge, Takashi Yoshimura, Kazuyoshi Koganemaru and Hiroshi Kitagaki*
Journal of the Institute of Brewing, 118, 3, 264-268 (2012)

19. Mitochondrial activity of sake brewery yeast affects malic and succinic acid production during alcoholic fermentation.
Saori Motomura, Kenta Horie and Hiroshi Kitagaki*
Journal of the Institute of Brewing, 118, 1, 22-26 (2012)

18. Improvement of tolerance of Saccharomyces cerevisiae to hot-compressed water-treated cellulose by expression of ADH1

Lahiru N. Jayakody, Kenta Horie, Nobuyuki Hayashi, and Hiroshi Kitagaki*
Applied Microbiology and Biotechnology, 94(1):273-83 (2012)
(highlighted as Key Scientific Article in Renewable Energy Global Innovations)
(Outstanding Scientific Presentation Award in International Congress on Yeasts, 2012)
国際微生物学連盟主催国際学会で優秀研究発表賞受賞、カナダの再生可能エネルギージャーナルでハイライト論文に選定

17. Detection and semi-quantitative analysis of sphingolipids contained in the shochu distillery waste.

Miyo Hirata, Yoshitaka Urano, Shigeki Inaba, Kazuyuki Kitatani, Toshiro Okazaki and Hiroshi Kitagaki*
J. Brew. Soc. Jpn., 106, 12, 848-853 (2011)

焼酎粕に含まれるスフィンゴ脂質の検出・半定量的評価とその由来の解析

平田みよ、浦野義崇、稲葉繁樹、北谷和之、岡崎俊朗、北垣浩志*
日本醸造学会誌、106, 12, 848-853 (2011) 

 

16. Breeding of a low pyruvate-producing ginjo sake yeast and its application to the fermentation industry.

        Makoto Sasaki, Takahiro Oba, HikaruSuenaga, Masae Sato, Hiromi Tsuruta, Keisuke Tsuge, Takeshi Yoshimura, Kazuyoshi Koganemaru and Hiroshi Kitagaki *

       Seibutsukogakukaishi, 、89, 5, 222-227 (2011)
吟醸酒製造用清酒酵母からのピルビン酸低生産株の育種と実製造でのピルビン酸およびαーアセト乳酸の低減
佐々木真、大場孝宏、末永光、稲橋正明、佐藤真佐恵、鶴田裕美、小林元太、柘植圭介、吉村臣史、小金丸和義、北垣浩志*
生物工学会誌、89, 5, 222-227 (2011)


15. Brewing characteristics of sake yeast resistant to an inhibitor of mitochondrial pyruvate transport on a pilot scale.

Miyo HIRATA, Saori MOTOMURA, Makoto Sasaki1, Kenta HORIE, Takahiro OBA, Keisuke TSUGE, Takeshi YOSHIMURA, Kazuyoshi KOGANEMARU and Hiroshi KITAGAKI *

     J. Brew. Soc. Jpn., 106, 5, 323-331 (2011)
ピルビン酸のミトコンドリア輸送阻害剤耐性酵母の小規模及び中規模パイロットスケールでの低アルコール清酒醸造特性
 平田みよ、元村沙織、佐々木真、堀江健太、大場孝宏、柘植圭介、吉村臣史、小金丸和義、北垣浩志*

日本醸造学会誌, 106, 5, 323-331 (2011)

 


14. Identification of glycolaldehyde as the key inhibitor of bioethanol fermentation by yeast and genome-wide analysis of its toxicity.
Lahiru N. Jayakody, Nobuyuki Hayashi* and Hiroshi Kitagaki*
Biotechnology Letters, 33(2):285-92 (2011)

13. Breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport.
Kenta Horie, Takahiro Oba, Saori Motomura, Atsuko Isogai, Takashi Yoshimura, Keisuke Tsuge, Kazuyoshi Koganemaru, Genta Kobayashi and Hiroshi Kitagaki*
Bioscience, Biotechnology, and Biochemistry, 74 (4), 843-847 (2010).(科学技術分野の文部科学大臣表彰(若手科学者賞))

12. ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in S.  
cerevisiae.

Hiroshi Kitagaki, Lauren Cowart, Nabil Matmati, David Montefusco, Jason Gandy, Silvia Vaena de Avalos, Sergei Novgorodov, Jim Zheng, Lina Obeid, Yusuf Hannun.

Journal of Biological Chemistry, 284, 10818-30 (2009)

11. Inhibition of mitochondrial fragmentation during sake brewing causes high malate production in sake yeast,

   Hiroshi Kitagaki*, Taku Kato, Atsuko Isogai, Shigeaki Mikami and Hitoshi Shimoi,

Journal of Bioscience and Bioengineering , 105, 675-678 (2008)(日本生物工学会・生物工学奨励賞(江田賞)、農学会・日本農学進歩賞, Selected as the cover)

 

10. Isc1 regulates sphingolipid metabolism in yeast mitochondria,

Hiroshi Kitagaki, Cowart LA, Matmati N, Vaena de Avalos S, Novgorodov SA, Zeidan YH, Bielawski J, Obeid LM, Hannun YA.

Biochmica BiophysicaActaBiomembranes, 1768, 2849-2861 (2007)

 

9.Mitochondrial dynamics of yeast during sake brewing,

Hiroshi Kitagaki* and Hitoshi Shimoi,

Journal of Bioscience and Bioengineering, 104, 227-30 (2007)

8.Ethanol-induced death in yeast exhibits features of apoptosis mediated by mitochondrial fission pathway,

Hiroshi Kitagaki*, Yoshio Araki, Kouichi Funato and Hitoshi Shimoi.

FEBS Letters, 581, 2935-2942 (2007)

 

7. Temperature sensitive dcw1 mutant is cell cycle-arrested with small buds which have aberrant cell walls,

Hiroshi Kitagaki, Kiyoshi Ito and Hitoshi Shimoi,

Eukaryotic Cell, 3, 1297-1306 (2004)

 

6. Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode GPI-anchored membrane proteins required for normal biosynthesis of the cell wall of Saccharomyces cerevisiae,

Hiroshi Kitagaki*, Hong Wu, Hitoshi Shimoi and Kiyoshi Ito,
Molecular Microbiology, 46, 1011-1022 (2002)

 

5. Autolysis of calpain large subunit inducing irreversible dissociation of stoichiometric heterodimer of calpain,

Hiroshi Kitagaki*, Shigeo Tomioka, Yoshizawa T, Sorimachi H, Saido TC, Ishiura S, Suzuki K.

Bioscience, Biotechnology and Biochemistry, 64, 689-695 (2000)


4. 1,1 -diphenyl-2-picrylhydrazyl radicals (DPPH) scavenging ability of sake during storage,
Hiroshi Kitagaki* and Mitsuaki Tsugawa,

Journal of Bioscience and Bioengineering, 87, 328- 332 (1999)(日本醸友会奨励賞)

 

3. Identification and analysis of a static culture-specific cell wall protein, Tir1p/Srp1p in Saccaromyces cerevisiae,

Hiroshi Kitagaki, Hitoshi Shimoi and Kiyoshi Ito

European Journal of Biochemistry (FEBS Journal) 249, 343-349 (1997)

 

  2. 清酒の製造工程におけるDPPH消去能の推移

北垣浩志*日本醸造協会誌 98, 589-593 (2003)

 

1. フリーラジカル消去能を高めたモデル清酒の官能評価

北垣浩志*岩槻安浩、津川光昭

日本醸造協会誌 、94, 502-506 (1999)

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